Principals of pharmacokinetics and drug compatibility: Basic understanding and how to deal with special conditions in the cardiac patient
ESPNIC Academy. Fonzo-Christe C. 09/11/15; 113556 Topic: Pharmacology
Disclosure(s): No disclosure
Learning Objectives
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After viewing this presentation the participant will be able to:
- Understand the impact of dosage on clearance and volume distribution
- Understand the impact of CYP2D6 polymorphism on codeine metabolism and relevance to breastfeeding
- Recognize the supoptimal exposure to some antibiotics due to augmented renal clearance in critically ill patients
- Identify potential drug-drug interactions and drug incompatibilities in neonates
- Discuss the dead space volume in continuous intravenous infusions using the plug-flow model
- Calculate the duration till new steady state with a different infusion
- Review ECMO patient factors implicated in drug administration and management
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